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Jennifer McCaffrey, Ph.D.

Continuing Education

  1. Good Laboratory Training Practices Training Course, February 10-11, 2005, Salt Lake City, UT
  2. Pharmacokinetics for Pharmaceutical Scientists Training Course, January 19-24, 2004, San Francisco, CA
  3. Transporters Workshop and Predictive ADME/Toxicology Conference, February 12, 2003, Philadelphia, PA

Invited Speaker Presentations

  1. Wisconsin State Annual Convention for American Assoc. of Univ. Women, Racine, WI, April, 1998.
  2. Michigan State Annual Convention for American Assoc. of Univ. Women, Troy, MI, May, 1997.
  3. Keystone Symposia: Ocular Cellular and Molecular Biology, Tamaron, CO, January, 1997.
  4. Small DNA Tumor Virus Meeting, Madison, WI, July, 1996.

Publications

  1. McCaffrey J, Yamasaki L, Dyson NJ, Harlow E, Griep AE, Disruption of retinoblastoma protein family function by human papillomavirus type 16 E7 oncoprotein inhibits lens development in part through E2F-1, Mol Cell Biol, 19(9): 6458-68,1999.
  2. Hamilton, JW, Kaltreider, RC, Bajenova, OV, Ihnat, MA, McCaffrey, J, Turpie, BW, Rowell, EE, Oh, J, Nemeth, MJ, Pesce, CA, Lariviere, JP. Molecular basis for effects of carcinogenic heavy metals in inducible gene expression. Environ Health Perspect, 106 Suppl 4:1005-15, 1998.
  3. Hamilton, JW, McCaffrey, J, Caron, RM, Louis, CA, Treadwell, MD and Hunt SR. Genotoxic chemical carcinogens target inducible genes in vivo. Ann. NY Acad. Sci., 726:343-345, 1994.
  4. McCaffrey, J, Wolf, CM, and Hamilton, JW. Effects of the genotoxic carcinogen chromium (VI) on basal and hormone-inducible phosphoenol-puruvate carboxykinase gene expression in vivo: correlation with glucocorticoid- and developmentally-regulated expression. Mol. Carcinog., 10:189-198, 1994.
  5. McCaffrey, J, and Hamilton, JW. Developmental regulation of basal and hormone-inducible phosphoenol-pyruvate carboxykinase gene expression in chick embryo liver in vivo. Arch.Of Biochem&Biophy, 309:10-17, 1994.
  6. McCaffrey, J and Hamilton, JW. Comparison of effects of direct-acting DNA methylating and ethylating agents on inducible gene expression in vivo, Env. & Mol. Mutagenesis, 23:164-170, 1994.
  7. Sinclair, J, McCaffrey, J, Sinclair, P, Bement, WJ, Lambrech, L, and Wood, S. Ethanol increases cytochromes P450IIE, IIB1/2 and IIIA in cultured rat hepatocytes, Arch. Of Biochem & Biophy, 284:360-365, 1991.
  8. Roebuck, BD, McCaffrey, J, and Baumgartner, K. Protective effects of voluntary exercise during the postinitiation phase of pancreatic carcinogenesis in the rat, Cancer Research, 50:6811-6816, 1990.

Poster Presentations

  1. Heybroek, M, Rule, G, Wells, DS, Pesyan, A and McCaffrey J, Identification and Quantitation of Isovaleramide Metabolites in Human Urine, American Association of Pharmaceutical Sciences, San Antonio, TX, 2006.
  2. Zahir, H, McCaffrey, J and Wells DS. Disposition of Isovaleramide in Rats and Dogs, International Society for the Study of Xenobiotics Annual Meeting, October 23 - 27, 2005, Maui, HI.
  3. Wang, H, Papac, DI, Wells, DS, Edwards, L, McLeod, D, McCaffrey, J, and Teuscher, N. NPS 100524 and 100525 - Two Potent and Selective Inhibitors of Human Cytochrome P450 1A1 and 1A2, International Society for the Study of Xenobiotics Annual Meeting, October 12 - 16, 2003, Providence RI.
  4. McCaffrey J, Selenka J, Neitzel S, and Tutko-Francisco, D. An LC/MS/MS Method for the Analysis and Identification of In-vitro Drug Metabolism Reaction Products, American Association of Pharmaceutical Sciences, New Orleans, LA, 1999.
  5. McCaffrey J, Yamasaki L, Harlow E, Dyson N, and Griep AE. Disruption of retinoblastoma protein function by HPV-16 E7 alters lens development in part through E2F-1, American Association of Cancer Research: Tumor Suppressor Gene Meeting, Victoria, BC, 1997.
  6. McCaffrey J, Yamasaki L, Harlow E, Dyson N, and Griep AE. Partial inhibition of HPV-16 E7 activities by an E2F1 null mutation, Keystone Symposia: Ocular Cellular and Molecular Biology, Tamaron, CO, 1997.
  7. McCaffrey J, Yamasaki L, Harlow E, Dyson N, and Griep AE. Partial inhibition of HPV-16 E7 activities by an E2F1 null mutation, Small DNA Tumor Virus Meeting, Madison, WI, 1996.
  8. McCaffrey J and Hamilton JW. The carcinogenic DNA cross-linking agent chromium(VI) alters hormonal regulation of phosphor-enol-pyruvate carboxykinase gene expression in vivo. American Association of Cancer Research, Orlando, FL, 1993.
  9. McCaffrey J and Hamilton, JW, Differential effects of methyl methanesulfonate on constitutive and inducible gene expression in vivo. Environmental Mutagen Society Annual Meeting, Orlando, FL, 1991.
  10. Caron RM, McCaffrey J and Hamilton JW, Targeting of inducible gene expression by carcinogens in vivo, American Association of Cancer Research, San Diego, CA, 1991.
  11. McCaffrey J, Roebuck BD and Baumgartner J, Protective effects of voluntary exercise during the post-initiation phase of pancreatic carcinogenesis, American Association of Cancer Research, San Francisco, CA, 1989.

Patents

  1. Prodrug Constructs of Pyrimidinone Compounds as Calcilytics, Shcherbakova, I, Wermuth, CG, Jeannot, F, Ciapetti, P, Roques, V, Jung, LM, Balandrin, MF, Nair, SK, Swierczek, K, McCaffrey, J, Heaton, WI, Breinholt, JA, Conklin, RL, Published on 22 June 2006, WO 2006/066070 A2.

 

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